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Article

[The Role of Macrophages in Repair of Injured Myocardium and Perspectives of Metabolic Reprogramming of Immune Cells for Myocardial Post-Infarction Recovery].

Kardiologiia - 1 Dec 2017

Stafeev I S, Menshikov M Y, Tkachuk V A, Parfenova E V

Abstract excerpt

A new trend in modern experimental cardiology is the development of approaches to correction of reparation after myocardial infarction (MI) with the use of specific effects on immune cells. One of the main targets for such interventions is the process of macrophage's polarization in the infarction zone. Proinflammatory M1‑macrophages contribute to hampered myocardial repair, in contrast to M2‑macrophages that...

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PMID: 29466211

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