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Article

Sirolimus alternative to blood transfusion as a life saver in blue rubber bleb nevus syndrome: A case report.

Medicine - 1 Feb 2018

Wang Ke-Ling, Ma Shu-Fang, Pang Ling-Yu, Zhang Meng-Na, Hu Lin-Yan, Liu Meng-Jia, Zou Li-Ping

Abstract excerpt

RATIONALE: Blue rubber bleb nevus syndrome (BRBNS) is a rare disease characterized by multiple venous malformations. The gastrointestinal bleeding and secondary iron deficiency anemia are the most common complications. There are currently no effective treatments for BRBNS. Here, we report a case of successful treatment with a small dose of sirolimus of a BRBN patient with a de novo gene mutation. PATIENT...

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Source

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Identifiers

PMID: 29465551
DOI: 10.1097/MD.0000000000009453
PMCID: PMC5841973

Genes

TEK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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