Article
Human papillomavirus (HPV) DNA triage of women with atypical squamous cells of undetermined significance with cobas 4800 HPV and Hybrid Capture 2 tests for detection of high-grade lesions of the uterine cervix.
Journal of clinical microbiology - 1 Apr 2012
Lapierre Simon Grandjean, Sauthier Philippe, Mayrand Marie-Hélène, Dufresne Simon, Petignat Patrick, Provencher Diane, Drouin Pierre, Gauthier Philippe, Dupuis Marie-Josée, Michon Bertrand, Ouellet Stéphan, Hadjeres Rachid, Ferenczy Alex, Franco Eduardo L, Coutlée François
Abstract excerpt
The triage of women with high-risk (HR) human papillomavirus (HPV)-positive smears for atypical squamous cells of undetermined significance (ASC-US) to colposcopy is now an integrated option in clinical guidelines. The performance of cobas 4800 HPV and that of Hybrid Capture 2 (HC2) for HR HPV DNA detection in cervical samples in PreservCyt were compared in 396 women referred to colposcopy for ASC-US. Of these,...
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