Article
Major Threat to Malaria Control Programs by Plasmodium falciparum Lacking Histidine-Rich Protein 2, Eritrea.
Emerging infectious diseases - 1 Mar 2018
Berhane Araia, Anderson Karen, Mihreteab Selam, Gresty Karryn, Rogier Eric, Mohamed Salih, Hagos Filmon, Embaye Ghirmay, Chinorumba Anderson, Zehaie Assefash, Dowd Simone, Waters Norman C, Gatton Michelle L, Udhayakumar Venkatachalam, Cheng Qin, Cunningham Jane
Abstract excerpt
False-negative results for Plasmodium falciparum histidine-rich protein (HRP) 2-based rapid diagnostic tests (RDTs) are increasing in Eritrea. We investigated HRP gene 2/3 (pfhrp2/pfhrp3) status in 50 infected patients at 2 hospitals. We showed that 80.8% (21/26) of patients at Ghindae Hospital and 41.7% (10/24) at Massawa Hospital were infected with pfhrp2-negative parasites and 92.3% (24/26) of patients at...
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