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Modeling Human Cardiac Hypertrophy in Stem Cell-Derived Cardiomyocytes

15 Feb 2018

Abstract excerpt

Cardiac hypertrophy accompanies many forms of cardiovascular diseases. The mechanisms behind the development and regulation of cardiac hypertrophy in the human setting are poorly understood, which can be partially attributed to the lack of a human cardiomyocyte-based preclinical test system recapitulating features of diseased myocardium. The objective of our study is to determine whether human embryonic stem...

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PMID: 29456183
DOI: 10.1016/j.stemcr.2018.01.016

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