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Article

The Perils of Single-Site Genetic Testing for Hereditary Cancer Syndromes in the Era of Next-Generation Sequencing.

The oncologist - 1 Apr 2018

Casasanta Nicole, Stark Elizabeth, McHenry Allison, Biagi Tara, Kaltman Rebecca

Abstract excerpt

A challenge in counseling patients with a family history suggesting a hereditary cancer syndrome is deciding which genetic tests or panels to order. In this article, we discuss the identification of multiple familial mutations through genetic counseling and panel testing. For patients meeting National Comprehensive Cancer Network criteria for clinical genetic testing, providers should consider expanded panels to...

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Source

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Identifiers

PMID: 29445031
DOI: 10.1634/theoncologist.2017-0372
PMCID: PMC5896713

Genes

ATM
BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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