Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).

doi:10.1186/s13195-017-0314-2

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Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE).

Alzheimer's research & therapy - 7 Feb 2018

Jessen Frank, Spottke Annika, Boecker Henning, Brosseron Frederic, Buerger Katharina, Catak Cihan, Fliessbach Klaus, Franke Christiana, Fuentes Manuel, Heneka Michael T, Janowitz Daniel, Kilimann Ingo, Laske Christoph, Menne Felix, Nestor Peter, Peters Oliver, Priller Josef, Pross Verena, Ramirez Alfredo, Schneider Anja, Speck Oliver, Spruth Eike Jakob, Teipel Stefan, Vukovich Ruth, Westerteicher Christine, Wiltfang Jens, Wolfsgruber Steffen, Wagner Michael, Düzel Emrah

Abstract excerpt

BACKGROUND: Deep phenotyping and longitudinal assessment of predementia at-risk states of Alzheimer's disease (AD) are required to define populations and outcomes for dementia prevention trials. Subjective cognitive decline (SCD) is a pre-mild cognitive impairment (pre-MCI) at-risk state of dementia, which emerges as a highly promising target for AD prevention. METHODS: The German Center for Neurodegenerative...

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PMID: 29415768
DOI: 10.1186/s13195-017-0314-2
PMCID: PMC5802096

Genes

SCD
APOE

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