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Modulation of Telomerase Activity in Cancer Cells by Dietary Compounds: A Review

6 Feb 2018

Abstract excerpt

Telomerase is expressed in ~90% of human cancer cell lines and tumor specimens, whereas its enzymatic activity is not detectable in most human somatic cells, suggesting that telomerase represents a highly attractive target for selective cancer treatment. Accordingly, various classes of telomerase inhibitors have been screened and developed in recent years. We and other researchers have successfully found that...

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PMID: 29415465
DOI: 10.3390/ijms19020478

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