Article
Correlation of in vitro sensitivity of chloroquine and other antimalarials with the partner drug resistance to Plasmodium falciparum malaria in selected sites of India.
Indian journal of medical microbiology - 1 Jan 2000
Sharma Supriya, Bharti Ram Suresh, Bhardwaj Nitin, Anvikar Anupkumar R, Valecha Neena, Mishra Neelima
Abstract excerpt
BACKGROUND: Antimalarial drug resistance is a potential threat for control and elimination of malaria. To ascertain the status of antimalarial drug resistance at the study sites, correlation between in vitro drug sensitivity pattern and drug resistance molecular markers in Plasmodium falciparum malaria was undertaken. MATERIALS AND METHODS: Polymorphisms in P. falciparum chloroquine resistance transporter (pfcrt)...
Topics
- Antimalarials
- Chloroquine
- Drug Resistance
- Genotype
- Genotyping Techniques
- Humans
- India
- Inhibitory Concentration 50
- Malaria, Falciparum
- Membrane Transport Proteins