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Article

Non-invasive perturbations of intracellular flow reveal physical principles of cell organization.

Nature cell biology - 1 Mar 2018

Mittasch Matthäus, Gross Peter, Nestler Michael, Fritsch Anatol W, Iserman Christiane, Kar Mrityunjoy, Munder Matthias, Voigt Axel, Alberti Simon, Grill Stephan W, Kreysing Moritz

Abstract excerpt

Recent advances in cell biology enable precise molecular perturbations. The spatiotemporal organization of cells and organisms, however, also depends on physical processes such as diffusion or cytoplasmic flows, and strategies to perturb physical transport inside cells are not yet available. Here, we demonstrate focused-light-induced cytoplasmic streaming (FLUCS). FLUCS is local, directional, dynamic, probe-free,...

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PMID: 29403036
DOI: 10.1038/s41556-017-0032-9

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