Article
RAS mutation prevalence among patients with metastatic colorectal cancer: a meta-analysis of real-world data.
Biomarkers in medicine - 1 Sept 2017
Kafatos George, Niepel Daniela, Lowe Kimberley, Jenkins-Anderson Sophie, Westhead Hal, Garawin Tamer, Traugottová Zuzana, Bilalis Antonios, Molnar Edit, Timar Jozsef, Toth Erika, Gouvas Nikolaos, Papaxoinis George, Murray Samuel, Mokhtar Nadia, Vosmikova Hana, Fabian Pavel, Skalova Alena, Wójcik Piotr, Tysarowski Andrzej, Barugel Mario, van Krieken J Han, Trojan Jörg
Abstract excerpt
AIM: A confirmed wild-type RAS tumor status is commonly required for prescribing anti-EGFR treatment for metastatic colorectal cancer. This noninterventional, observational research project estimated RAS mutation prevalence from real-world sources. MATERIALS & METHODS: Aggregate RAS mutation data were collected from 12 sources in three regions. Each source was analyzed separately; pooled prevalence estimates were...
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