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Article

A highly efficient murine model of experimental myopia.

Scientific reports - 1 Feb 2018

Jiang Xiaoyan, Kurihara Toshihide, Kunimi Hiromitsu, Miyauchi Maki, Ikeda Shin-Ichi, Mori Kiwako, Tsubota Kinya, Torii Hidemasa, Tsubota Kazuo

Abstract excerpt

Despite the global pandemic of myopia, the precise molecular mechanism of the onset of myopia remains largely unknown. This is partially because of the lack of efficient murine myopic models that allow genetic manipulation at low cost. Here we report a highly practical and reproducible lens-induced myopia model by specially designed frames and lenses for mice. A lens power dependent myopic induction in mice was...

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Identifiers

PMID: 29391484
DOI: 10.1038/s41598-018-20272-w
PMCID: PMC5794929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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