Article
Benefit of Preemptive Pharmacogenetic Information on Clinical Outcome.
Clinical pharmacology and therapeutics - 1 May 2018
Roden Dan M, Van Driest Sara L, Mosley Jonathan D, Wells Quinn S, Robinson Jamie R, Denny Joshua C, Peterson Josh F
Abstract excerpt
The development of new knowledge around the genetic determinants of variable drug action has naturally raised the question of how this new knowledge can be used to improve the outcome of drug therapy. Two broad approaches have been taken: a point-of-care approach in which genotyping for specific variant(s) is undertaken at the time of drug prescription, and a preemptive approach in which multiple genetic variants...
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