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Article

Autophagy and Longevity.

31 Jan 2018

Abstract excerpt

Autophagy is an evolutionally conserved cytoplasmic degradation system in which varieties of materials are sequestered by a double membrane structure, autophagosome, and delivered to the lysosomes for the degradation. Due to the wide varieties of targets, autophagic activity is essential for cellular homeostasis. Recent genetic evidence indicates that autophagy has a crucial role in the regulation of animal...

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PMID: 29370695
DOI: 10.14348/molcells.2018.2333

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