Article
Genome-wide scan for circulating vascular adhesion protein-1 levels: MACROD2 as a potential transcriptional regulator of adipogenesis.
Journal of diabetes investigation - 1 Sept 2018
Chang Yi-Cheng, Hee Siow-Wey, Lee Wei-Jei, Li Hung-Yuan, Chang Tien-Jyun, Lin Ming-Wei, Hung Yi-Jen, Lee I-Te, Hung Kuan-Yi, Assimes Themistocles, Knowles Joshua W, Nong Jiun-Yi, Lee Po-Chu, Chiu Yen-Feng, Chuang Lee-Ming
Abstract excerpt
AIMS/INTRODUCTION: Vascular adhesion protein-1 (VAP-1) is a membrane-bound amine oxidase highly expressed in mature adipocytes and released into the circulation. VAP-1 has been strongly implicated in several pathological processes, including diabetes, inflammation, hypertension, hepatic steatosis and renal diseases, and is an important disease marker and therapeutic target. Here, we aimed to identify the genetic...
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