Widespread modulation of gene expression by copy number variation in skeletal muscle.

doi:10.1038/s41598-018-19782-4

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Article

Widespread modulation of gene expression by copy number variation in skeletal muscle.

Scientific reports - 23 Jan 2018

Geistlinger Ludwig, da Silva Vinicius Henrique, Cesar Aline Silva Mello, Tizioto Polyana Cristine, Waldron Levi, Zimmer Ralf, Regitano Luciana Correia de Almeida, Coutinho Luiz Lehmann

Abstract excerpt

Copy number variation (CNV) is a frequently observed deviation from the diploid state due to duplication or deletion of genomic regions. Although intensively analyzed for association with diseases and production traits, the specific mechanisms and extent by which such variations affect the phenotype are incompletely understood. We present an integrative study on CNV and genome-wide gene expression in Brazilian...

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Identifiers

PMID: 29362391
DOI: 10.1038/s41598-018-19782-4
PMCID: PMC5780461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.