Article
Identification of copy number variation in French dairy and beef breeds using next-generation sequencing.
Genetics, selection, evolution : GSE - 24 Oct 2017
Letaief Rabia, Rebours Emmanuelle, Grohs Cécile, Meersseman Cédric, Fritz Sébastien, Trouilh Lidwine, Esquerré Diane, Barbieri Johanna, Klopp Christophe, Philippe Romain, Blanquet Véronique, Boichard Didier, Rocha Dominique, Boussaha Mekki
Abstract excerpt
BACKGROUND: Copy number variations (CNV) are known to play a major role in genetic variability and disease pathogenesis in several species including cattle. In this study, we report the identification and characterization of CNV in eight French beef and dairy breeds using whole-genome sequence data from 200 animals. Bioinformatics analyses to search for CNV were carried out using four different but complementary...
Topics
- Animals
- Cattle
- DNA Copy Number Variations
- Dairy Products
- Genome-Wide Association Study
- High-Throughput Nucleotide Sequencing
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Quantitative Trait, Heritable