Article
Compositional and functional variations of oral microbiota associated with the mutational changes in oral cancer.
Oral oncology - 1 Feb 2018
Yang Shun-Fa, Huang Hsien-Da, Fan Wen-Lang, Jong Yuh-Jyh, Chen Mu-Kuan, Huang Chien-Ning, Chuang Chun-Yi, Kuo Yu-Lun, Chung Wen-Hung, Su Shih-Chi
Abstract excerpt
OBJECTIVES: Both genetic and environmental factors are conceivably required to assess the prognosis of oral squamous cell carcinoma (OSCC), yet little is known regarding the relationship between oral microbiome and the mutational spectrum of OSCC. MATERIALS AND METHODS: Here, we used 16S rRNA amplicon sequencing to study the composition of oral microorganisms in OSCC patients, whose cancer mutational profiles...
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