Article
Mutation screening of INS and KCNJ11 genes in Taiwanese children with type 1B diabetic onset before the age of 5 years.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Aug 2018
Lo Fu-Sung
Abstract excerpt
Type 1 diabetes (T1D) is caused by β-cell destruction, usually leading to absolute insulin deficiency. T1D is a heterogeneous disease and is divided into two subtypes according to the presence or absence of pancreatic autoantibodies: type 1A (immune mediated) and type 1B (idiopathic). Genes such as KCNJ11 or INS, which play key roles in β-cell function, provide some insight into the pathogenesis of type 1B...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
