Article
PD-1/PD-L1 Axis in Lung Cancer.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Santini Fernando C, Hellmann Matthew D
Abstract excerpt
Cancer immunotherapies have revolutionized the treatment of non-small cell lung cancer. Yet, only a small subset of patients will benefit from PD-1 or PD-L1 blockade. PD-L1 tumor cell expression is the only approved biomarker at present. Tumor mutational burden and other emerging biomarkers should improve patient selection. Combination therapy approaches with chemotherapy or cytotoxic T-lymphocyte-associated...
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