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Article

Comparison of lesional skin c-KIT mutations with clinical phenotype in patients with mastocytosis.

Clinical and experimental dermatology - 1 Jun 2018

Chan I J, Tharp M D

Abstract excerpt

BACKGROUND: Activating c-KIT mutations cause abnormal mast cell growth and appear to play a role in mastocytosis. However, the correlation of c-KIT mutations with disease phenotypes is poorly characterized. AIM: To evaluate the correlation of c-KIT mutations with clinical presentations and laboratory findings. METHODS: Total cellular RNA was isolated from the skin lesions of 43 adults and 7 children with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29350409
DOI: 10.1111/ced.13362

Genes

KIT

Variants

Provenance

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