Article
Pure mechanistic analysis of additive neuroprotective effects between baicalin and jasminoidin in ischemic stroke mice.
Acta pharmacologica Sinica - 1 Jun 2018
Wang Peng-Qian, Liu Qiong, Xu Wen-Juan, Yu Ya-Nan, Zhang Ying-Ying, Li Bing, Liu Jun, Wang Zhong
Abstract excerpt
Both baicalin (BA) and jasminoidin (JA) are active ingredients in Chinese herb medicine Scutellaria baicalensis and Fructus gardeniae, respectively. They have been shown to exert additive neuroprotective action in ischemic stroke models. In this study we used transcriptome analysis to explore the pure therapeutic mechanisms of BA, JA and their combination (BJ) contributing to phenotype variation and reversal of...
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