Article
A new hepatitis B virus e antigen-negative strain gene used as a reference sequence in an animal model.
Biochemical and biophysical research communications - 5 Feb 2018
Cao Min, Zhao Zhonghua, Tang Yuwei, Wei Qinglv, Wang Lei, Xiang Qin, Zhang Yunmei, Zhang Huatang, Lai Guoqi
Abstract excerpt
Infection with hepatitis B virus (HBV) e-antigen (HBeAg)-negative strains is increasingly prevalent. Currently, detailed information of the obtained natural HBV strain is not available except for the B genotype and HBeAg-negative. The aim of the present study was to characterize the natural genetic variation of the HBeAg-negative strain and investigate its function. The genic sequence was determined using Sanger...
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