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Article

Chemical conversion of human lung fibroblasts into neuronal cells.

International journal of molecular medicine - 1 Mar 2018

Wan Xiao-Yu, Xu Li-Yun, Li Bing, Sun Qiu-Hong, Ji Qiu-Liang, Huang Dong-Dong, Zhao Lan, Xiao Yong-Tao

Abstract excerpt

It has been previously reported that human embryonic fibroblasts and mouse embryonic fibroblasts can be converted into neuronal cells using chemical agents, along with forced expression specific transcriptional factors. However, the materials required for reprogramming in these approaches presents major technical difficulties and safety concerns. The current study investigated whether a cocktail of small...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29328434
DOI: 10.3892/ijmm.2018.3375
PMCID: PMC5819915

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