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Article

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

Molecular psychiatry - 1 Feb 2019

Hill W D, Marioni R E, Maghzian O, Ritchie S J, Hagenaars S P, McIntosh A M, Gale C R, Davies G, Deary I J

Abstract excerpt

Intelligence, or general cognitive function, is phenotypically and genetically correlated with many traits, including a wide range of physical, and mental health variables. Education is strongly genetically correlated with intelligence (rg = 0.70). We used these findings as foundations for our use of a novel approach-multi-trait analysis of genome-wide association studies (MTAG; Turley et al. 2017)-to combine two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29326435
DOI: 10.1038/s41380-017-0001-5
PMCID: PMC6344370

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