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Article

Analysis of MTR and MTRR Gene Polymorphisms in Chinese Patients With Ventricular Septal Defect.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2000

Su Jiang, Li Zhongzhi

Abstract excerpt

BACKGROUND: Congenital heart defects (CHDs) are the most common birth defects and ventricular septal defects (VSDs) are one of the most common types of CHDs. Genes involved in homocysteine/folate metabolism may play important roles in CHDs. Methionine synthase and methionine synthase reductase (MTRR) are key regulatory enzymes involved in the metabolic pathway of homocysteine. METHODS: We investigated whether a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29293099
DOI: 10.1097/PAI.0000000000000512
PMCID: PMC6250295

Genes

MTRR
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

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Analysis of MTR and MTRR Gene Polymorphisms in Chinese Patients With Ventricular Septal Defect.PMID 29293099Read ↗

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Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han populationSemantic proximity Read ↗

Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population.Semantic proximity Read ↗

Genetic polymorphisms in MTR are associated with non-syndromic congenital heart disease from a family-based case-control study in the Chinese populationSemantic proximity Read ↗

Risk of congenital heart defects is influenced by genetic variation in folate metabolism.Semantic proximity Read ↗

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MTRR 66A>G polymorphism in relation to congenital heart defects.Semantic proximity Read ↗

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