Article
Molecular analysis of a serotype 8 human astrovirus genome.
The Journal of general virology - 1 Dec 2000
Méndez-Toss Martha, Romero-Guido Pedro, Munguía Maria Elena, Méndez Ernesto, Arias Carlos F
Abstract excerpt
Human astroviruses are an important cause of gastroenteritis. As part of a molecular epidemiological study carried out in Mexico a human astrovirus isolate, Yuc-8, was adapted to grow in CaCo-2 cells, and its entire genome was sequenced. A 15 amino acid deletion in ORF1a, which has been associated with adaptation of astroviruses to grow in cells other than CaCo-2, was present in Yuc-8. Comparative sequence...
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