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Article

Characterization of different osteoclast phenotypes in the progression of bone invasion by oral squamous cell carcinoma.

Oncology reports - 1 Mar 2018

Quan Jingjing, Hou Yuluan, Long Weiling, Ye Shu, Wang Zhiyuan

Abstract excerpt

The present study aimed to characterize different phenotypes of osteoclasts in the progression of bone invasion by oral squamous cell carcinoma (OSCC). A local bone invasion model of OSCC was established by injecting SCC25 human OSCC cells into the center of calvariae in nude mice, and all mice were found to have a typical bone resorption area. Staining for tartrate-resistant acid phosphatase (TRAP) revealed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29286135
DOI: 10.3892/or.2017.6166
PMCID: PMC5802026

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