Article
The effects of CXCL10 polymorphisms on COPD susceptibility.
Molecular genetics and genomics : MGG - 1 Jun 2018
Wang Yan, Zhou Qipeng, Dong Lian, Xiong Mingmei, Jiang Hua, Guo Meihua, Zhao Li, Yuan Liang, Li Ziying, Liu Hanwei, Wang Jian, Zhong Nanshan, Lu Wenju
Abstract excerpt
The polymorphisms of cytokine genes has been reported to modulate the individual's susceptibility to environmental stimuli in COPD development. C-X-C motif chemokine 10 (CXCL10) mediates recruitment inflammatory cells such as monocytes. Therefore, it may play a key role in COPD. Here, a case-control study was conducted to evaluate the association between CXCL10 tag-SNPs and COPD risk. Four tag-SNPs including...
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