Article
Functional and phenotypical analysis of IL-6-secreting CD4+ T cells in human adipose tissue.
European journal of immunology - 1 Mar 2018
de Jong Anja J, Pollastro Sabrina, Kwekkeboom Joanneke C, Andersen Stefan N, Dorjée Annemarie L, Bakker Aleida M, Alzaid Fawaz, Soprani Antoine, Nelissen Rob G H H, Mullers Jan B, Venteclef Nicolas, de Vries Niek, Kloppenburg Margreet, Toes René E M, Ioan-Facsinay Andreea
Abstract excerpt
Emerging evidence indicates that a dynamic interplay between the immune system and adipocytes contributes to the disturbed homeostasis in adipose tissue of obese subjects. Recently, we observed IL-6-secretion by CD4+ T cells from the stromal vascular fraction (SVF) of the infrapatellar fat pad (IFP) of knee osteoarthritis patients directly ex vivo. Here we show that human IL-6+ CD4+ T cells from SVF display a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.