Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

First preimplantation genetic testing case for monogenic disease in Latvia.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jan 2017

Perminov Dmitry, Voložonoka Ludmila, Korņejeva Liene, Jokste-Pțmane Evija, Blumberga Arita, Krasucka Sandra, Seimuškina Nellija, Kovaļova Irina, Fodina Violeta

Abstract excerpt

Huntington's disease (HD) is fatal neurodegenerative disease caused by a (CAG) triplet repeat expansion in the Huntingtin (HTT) gene. Inheritance pattern of the disease is autosomal dominant and onset depending on triplet repeat count. Transgenerational HD transmission can be avoided by preimplantation genetic diagnosis (PGD). Here, we report the first preimplantation genetic testing case for monogenic disease,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Huntingtin Protein

Share to Huntington Disease

Share to Latvia

Share to Ovulation Induction

Share to Pregnancy

Share to Preimplantation Diagnosis

Source

Identifiers

PMID: 29264979
DOI: 10.1080/09513590.2017.1404239

Genes

HTT
PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

First preimplantation genetic testing case for monogenic disease in Latvia.PMID 29264979Read ↗

Preimplantation genetic diagnosis.Semantic proximity Read ↗

Preimplantation Genetic Testing for Adult-Onset Neurodegenerative DiseaseSemantic proximity Read ↗

Experience of more than 100 preimplantation genetic diagnosis cycles for monogenetic diseases using whole genome amplification and linkage analysis in a single centre.Semantic proximity Read ↗

Robust Preimplantation Genetic Testing of Huntington Disease by Combined Triplet-Primed PCR Analysis of the HTT CAG Repeat and Multi-Microsatellite Haplotyping.Semantic proximity Read ↗

Genetic counseling and testing for Huntington's disease: A historical reviewSemantic proximity Read ↗

Predictive and pre-natal testing for Huntington Disease in Australia: results and challenges encountered during a 10-year period (1994-2003).Semantic proximity Read ↗

Preimplantation diagnosis for Huntington's disease (HD): clinical application and analysis of the HD expansion in affected embryos.Semantic proximity Read ↗

Preimplantation genetic diagnosis for Huntington's disease with exclusion testingSemantic proximity Read ↗

Preimplantation genetic testing for monogenic disorders (PGT-M) offers an alternative strategy to prevent children from being born with hereditary neurological diseases or metabolic diseases dominated by nervous system phenotypes: a retrospective study.Semantic proximity Read ↗

Huntington's disease.Semantic proximity Read ↗

Recommendations for the predictive genetic test in Huntington's diseaseSemantic proximity Read ↗

Molecular diagnosis of Huntington disease in Portugal: implications for genetic counselling and clinical practice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.