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Article

Effects of mutation and selection on plasticity of a promoter activity in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 26 Dec 2017

Duveau Fabien, Yuan David C, Metzger Brian P H, Hodgins-Davis Andrea, Wittkopp Patricia J

Abstract excerpt

Phenotypic plasticity is an evolvable property of biological systems that can arise from environment-specific regulation of gene expression. To better understand the evolutionary and molecular mechanisms that give rise to plasticity in gene expression, we quantified the effects of 235 single-nucleotide mutations in the Saccharomyces cerevisiae TDH3 promoter (PTDH3 ) on the activity of this promoter in media...

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Identifiers

PMID: 29259117
DOI: 10.1073/pnas.1713960115
PMCID: PMC5748197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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