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Article

Deciphering Multifactorial Resistance Phenotypes in Acinetobacter baumannii by Genomics and Targeted Label-free Proteomics.

Molecular & cellular proteomics : MCP - 1 Mar 2018

Cecchini Tiphaine, Yoon Eun-Jeong, Charretier Yannick, Bardet Chloé, Beaulieu Corinne, Lacoux Xavier, Docquier Jean-Denis, Lemoine Jerome, Courvalin Patrice, Grillot-Courvalin Catherine, Charrier Jean-Philippe

Abstract excerpt

Resistance to β-lactams in Acinetobacter baumannii involves various mechanisms. To decipher them, whole genome sequencing (WGS) and real-time quantitative polymerase chain reaction (RT-qPCR) were complemented by mass spectrometry (MS) in selected reaction monitoring mode (SRM) in 39 clinical isolates. The targeted label-free proteomic approach enabled, in one hour and using a single method, the quantitative...

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Identifiers

PMID: 29259044
DOI: 10.1074/mcp.RA117.000107
PMCID: PMC5836370

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SRM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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