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Article

Asthma versus chronic obstructive pulmonary disease, the Dutch versus British hypothesis, and role of interleukin-5.

Current opinion in allergy and clinical immunology - 1 Feb 2018

Chambliss Jeffrey M, Sur Sanjiv, Tripple Julia W

Abstract excerpt

PURPOSE OF REVIEW: Asthma and COPD represent heterogeneous disorders with broad ranging impact on patients and health systems. This review focuses on evidence for early attempts at understanding their pathogenesis by the British and Dutch hypotheses. It also addresses the role of eosinophils, IL-5, and biologics targeting these pathways in asthma and COPD. RECENT FINDINGS: Among asthma and COPD patients, clusters...

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Identifiers

PMID: 29257776
DOI: 10.1097/ACI.0000000000000409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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