Article
Formation of large viroplasms and virulence of Cauliflower mosaic virus in turnip plants depend on the N-terminal EKI sequence of viral protein TAV.
PloS one - 1 Jan 2017
Geldreich Angèle, Haas Gabrielle, Kubina Julie, Bouton Clément, Tanguy Mélanie, Erhardt Mathieu, Keller Mario, Ryabova Lyubov, Dimitrova Maria
Abstract excerpt
Cauliflower mosaic virus (CaMV) TAV protein (TransActivator/Viroplasmin) plays a pivotal role during the infection cycle since it activates translation reinitiation of viral polycistronic RNAs and suppresses RNA silencing. It is also the major component of cytoplasmic electron-dense inclusion bodies (EDIBs) called viroplasms that are particularly evident in cells infected by the virulent CaMV Cabb B-JI isolate....
Topics
- Amino Acid Motifs
- Amino Acid Sequence
- Brassica napus
- Caulimovirus
- Inclusion Bodies, Viral
- Mutant Proteins
- Phenotype
- Protein Domains
- Protoplasts
- Reverse Transcription
- Structure-Activity Relationship
- Trans-Activators
- Virulence