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Article

A polygenic score for schizophrenia predicts glycemic control.

Translational psychiatry - 18 Dec 2017

Cao Han, Chen Junfang, Meyer-Lindenberg Andreas, Schwarz Emanuel

Abstract excerpt

Schizophrenia is substantially comorbid with type 2 diabetes (T2D), but the molecular basis of this effect is incompletely understood. Here, we show that a cortical schizophrenia expression score predicts glycemic control from pancreatic islet cell expression. We used machine learning to identify a cortical expression signature in 212 schizophrenia patients and controls, which explained ~25% of the...

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Identifiers

PMID: 29249829
DOI: 10.1038/s41398-017-0044-z
PMCID: PMC5802590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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