Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Understanding childhood diabetes mellitus: new pathophysiological aspects.

Journal of inherited metabolic disease - 1 Jan 2018

Grulich-Henn Juergen, Klose Daniela

Abstract excerpt

Diabetes mellitus (DM) is not a single disease, but several pathophysiological conditions where synthesis, release, and/or action of insulin are disturbed. A progressive autoimmune/autoinflammatory destruction of islet cells is still considered the main pathophysiological event in the development of T1DM, but there is evidence that T1DM itself is a heterogeneous disease. More than 50 gene regions are closely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoimmunity
Share to Blood Glucose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Diabetes Mellitus, Type 1

Share to Energy Metabolism

Share to Infant, Newborn, Diseases

Share to Islets of Langerhans

Source

Identifiers

PMID: 29247329
DOI: 10.1007/s10545-017-0120-9

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Understanding childhood diabetes mellitus: new pathophysiological aspects.PMID 29247329Read ↗

Current insights into the genetic basis of diabetes mellitus in children and adolescents.Semantic proximity Read ↗

[Monogenic diabetes : a pioneer in precision medicine management].Semantic proximity Read ↗

Type 1 diabetes: current concepts in epidemiology, pathophysiology, clinical care, and research.Semantic proximity Read ↗

Maturity-onset diabetes of the young (MODY) - in search of ideal diagnostic criteria and precise treatment.Semantic proximity Read ↗

Insights into the Genetics and Signaling Pathways in Maturity-Onset Diabetes of the Young.Semantic proximity Read ↗

Maturity-onset diabetes of the young: From a molecular basis perspective toward the clinical phenotype and proper management.Semantic proximity Read ↗

Diabetes mellitus: The epidemic of the centurySemantic proximity Read ↗

Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment.Semantic proximity Read ↗

Breakthroughs in monogenic diabetes genetics: from pediatric forms to young adulthood diabetes.Semantic proximity Read ↗

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.Semantic proximity Read ↗

The lessons of early-onset monogenic diabetes for the understanding of diabetes pathogenesis.Semantic proximity Read ↗

Pathogenesis of Type 1 Diabetes: Established Facts and New Insights.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.