Article
The evolutionary fate of heterogeneous gene duplications: A precarious overdominant equilibrium between environment, sublethality and complementation.
Molecular ecology - 1 Jan 2018
Milesi Pascal, Assogba Benoît S, Atyame Célestine M, Pocquet Nicolas, Berthomieu Arnaud, Unal Sandra, Makoundou Patrick, Weill Mylène, Labbé Pierrick
Abstract excerpt
Gene duplications occur at a high rate. Although most appear detrimental, some homogeneous duplications (identical gene copies) can be selected for beneficial increase in produced proteins. Heterogeneous duplications, which combine divergent alleles of a single locus, are seldom studied due to the paucity of empirical data. We investigated their role in an ongoing adaptive process at the ace-1 locus in Culex...
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