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High-Resolution Single-Cell Sequencing of Malaria Parasites.

Genome biology and evolution - 1 Dec 2017

Trevino Simon G, Nkhoma Standwell C, Nair Shalini, Daniel Benjamin J, Moncada Karla, Khoswe Stanley, Banda Rachel L, Nosten François, Cheeseman Ian H

Abstract excerpt

Single-cell genomics is a powerful tool for determining the genetic architecture of complex communities of unicellular organisms. In areas of high transmission, malaria patients are often challenged by the activities of multiple Plasmodium falciparum lineages, which can potentiate pathology, spread drug resistance loci, and also complicate most genetic analysis. Single-cell sequencing of P. falciparum would be...

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Identifiers

PMID: 29220419
DOI: 10.1093/gbe/evx256
PMCID: PMC5737330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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