Article
A PLAG1 mutation contributed to stature recovery in modern cattle.
Scientific reports - 7 Dec 2017
Utsunomiya Yuri Tani, Milanesi Marco, Utsunomiya Adam Taiti Harth, Torrecilha Rafaela Beatriz Pintor, Kim Eui-Soo, Costa Márcio Silva, Aguiar Tamíris Sayuri, Schroeder Steven, do Carmo Adriana Santana, Carvalheiro Roberto, Neves Haroldo Henrique Rezende, Padula Romulo Cláudio Morozini, Sussai Thayla Souza, Zavarez Ludmilla Balbo, Cipriano Rafael Silva, Caminhas Maria Margareth Theodoro, Hambrecht George, Colli Licia, Eufemi Elisa, Ajmone-Marsan Paolo, Cesana Deneb, Sannazaro Marco, Buora Maurizio, Morgante Michele, Liu George, Bickhart Derek, Van Tassell Curtis Paul, Sölkner Johann, Sonstegard Tad Stewart, Garcia José Fernando
Abstract excerpt
The recent evolution of cattle is marked by fluctuations in body size. Height in the Bos taurus lineage was reduced by a factor of ~1.5 from the Neolithic to the Middle Ages, and increased again only during the Early Modern Ages. Using haplotype analysis, we found evidence that the bovine PLAG1 mutation (Q) with major effects on body size, weight and reproduction is a >1,000 years old derived allele that...
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