Article
miR-33a hinders the differentiation of adipose mesenchymal stem cells towards urothelial cells in an inductive condition by targeting β‑catenin and TGFR.
Molecular medicine reports - 1 Feb 2018
Fan Gang, Xu Zhenzhou, Hu Xiang, Li Mingfeng, Zhou Jie, Zeng Yong, Xie Yu
Abstract excerpt
Tissue engineering technology offers an appealing approach for tissue reconstruction of the urothelium. Adipose‑derived mesenchymal stem cells (ADSCs) represent an abundant source for tissue engineering applications. However, ASCs primarily possess mesoderm lineage differentiation potential. It is difficult to induce differentiation of ASCs towards urothelial cells that are derived from the endoderm, although a...
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