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Article

Screening in GI Cancers: The Role of Genetics.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2015

Stoffel Elena M

Abstract excerpt

Genetic and epigenetic alterations identified in tumors of different cancer types can provide insights regarding the roles played by different cell signaling pathways in carcinogenesis. Somatic mutation profiles of GI tumors are used to guide choice of chemotherapy and can facilitate identification of individuals whose cancers arise in the setting of genetic predisposition. This review provides a framework for...

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Biomarkers, Tumor
Early Detection of Cancer
Epigenesis, Genetic
Gastrointestinal Neoplasms
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Precision Medicine

Predictive Value of Tests

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PMID: 25918283
DOI: 10.1200/JCO.2014.60.6764

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