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Article

Spatially Resolved and Quantitative Analysis of VISTA/PD-1H as a Novel Immunotherapy Target in Human Non-Small Cell Lung Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2018

Villarroel-Espindola Franz, Yu Xiaoqing, Datar Ila, Mani Nikita, Sanmamed Miguel, Velcheti Vamsidhar, Syrigos Konstantinos, Toki Maria, Zhao Hongyu, Chen Lieping, Herbst Roy S, Schalper Kurt A

Abstract excerpt

Purpose: Determine the localized expression pattern and clinical significance of VISTA/PD-1H in human non-small cell lung cancer (NSCLC).Experimental Design: Using multiplex quantitative immunofluorescence (QIF), we performed localized measurements of VISTA, PD-1, and PD-L1 protein in 758 stage I-IV NSCLCs from 3 independent cohorts represented in tissue microarray format. The targets were selectively measured in...

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Source

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Identifiers

PMID: 29203588
DOI: 10.1158/1078-0432.CCR-17-2542
PMCID: PMC5884702

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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