Article
Further Studies of Unsuspected Emphysema in Nonsmoking Patients With Asthma With Persistent Expiratory Airflow Obstruction.
Chest - 1 Mar 2018
Gelb Arthur F, Yamamoto Alfred, Verbeken Eric K, Schein Mark J, Moridzadeh Roxanna, Tran Diem, Fraser Christine, Barbers Richard, Elatre Wafaa, Koss Michael N, Glassy Eric F, Nadel Jay A
Abstract excerpt
BACKGROUND: Previously, we and other investigators have described reversible loss of lung elastic recoil in patients with acute and persistent, moderate-to-severe, chronic, treated asthma who never smoked, and its adverse effect on maximal expiratory airflow. In four consecutive autopsies, we reported the pathophysiologic mechanism(s) has been unsuspected mild, diffuse, middle and upper lobe centrilobular...
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