Article
Mapping causal mutations by exome sequencing in a wheat TILLING population: a tall mutant case study.
Molecular genetics and genomics : MGG - 1 Apr 2018
Mo Youngjun, Howell Tyson, Vasquez-Gross Hans, de Haro Luis Alejandro, Dubcovsky Jorge, Pearce Stephen
Abstract excerpt
Forward genetic screens of induced mutant plant populations are powerful tools to identify genes underlying phenotypes of interest. Using traditional techniques, mapping causative mutations from forward screens is a lengthy, multi-step process, requiring the identification of a broad genetic region followed by candidate gene sequencing to characterize the causal variant. Mapping by whole genome sequencing...
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