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Developmental origins of health and disease: current knowledge and potential mechanisms

29 Aug 2017

Abstract excerpt

Epidemiologic and clinical research has provided a large body of evidence supporting the developmental origins of health and disease (DOHaD), but there has been a relative dearth of mechanistic studies in humans due to the complexity of working with large, longitudinal cohorts. Nonetheless, animal models of undernutrition have provided substantial evidence for the potential epigenetic, metabolic, and endocrine...

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PMID: 29186623
DOI: 10.1093/nutrit/nux053

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