Article
Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans.
Obesity (Silver Spring, Md.) - 1 Jan 2018
Gao Chuan, Langefeld Carl D, Ziegler Julie T, Taylor Kent D, Norris Jill M, Chen Yii-Der I, Hellwege Jacklyn N, Guo Xiuqing, Allison Matthew A, Speliotes Elizabeth K, Rotter Jerome I, Bowden Donald W, Wagenknecht Lynne E, Palmer Nicholette D
Abstract excerpt
OBJECTIVE: This study aimed to explore the genetic mechanisms of regional fat deposition, which is a strong risk factor for metabolic diseases beyond total adiposity. METHODS: A genome-wide association study of 7,757,139 single-nucleotide polymorphisms (SNPs) in 983 Mexican Americans (nmale = 403; nfemale = 580) from the Insulin Resistance Atherosclerosis Family Study was performed. Association analyses were...
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