Article
Computational derivation of a molecular framework for hair follicle biology from disease genes.
Scientific reports - 24 Nov 2017
Severin Rachel K, Li Xinwei, Qian Kun, Mueller Andreas C, Petukhova Lynn
Abstract excerpt
Knowledge about genetic drivers of disease increases the efficiency of interpreting patient DNA sequence and helps to identify and prioritize biological points of intervention. Discoveries of genes with single mutations exerting substantial phenotypic impact reliably provide new biological insight, although such approaches tend to generate knowledge that is disjointed from the complexity of biological systems...
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