Article
Molecular network-selected pharmacogenomics in a case of bipolar spectrum disorder.
Pharmacogenomics - 1 Dec 2017
Fortinguerra Stefano, Buriani Alessandro, Sorrenti Vincenzo, Lenzi Michele, Giusti Pietro
Abstract excerpt
Personal genomic analysis was used for molecular diagnosis and pharmacogenomics in a 53-year-old female suffering from alternating depressive and dysphoric episodes. A total of 52 genes and 108 SNPs were analyzed in the whole genome. Results from the pharmacogenomic analysis were consistent with the pharmacological history and indicate mutations associated with low monoaminergic tone, but also a hyperactive 5HT2A...
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