Article
Correlation between entecavir penetration in peripheral blood mononuclear cells and HBV DNA decay during treatment of HBeAg-negative chronic hepatitis B.
Antiviral therapy - 1 Jan 2018
De Nicolò Amedeo, Boglione Lucio, Cusato Jessica, Fatiguso Giovanna, Favata Fabio, Allegra Sarah, Cariti Giuseppe, Di Perri Giovanni, D'Avolio Antonio
Abstract excerpt
BACKGROUND: Recently, due to its high effectiveness and tolerability, the treatment of chronic hepatitis B with entecavir became a standard practice. However, limited knowledge is currently available about its pharmacokinetic behaviour and intracellular disposition. Recently, our group reported an inverse correlation between entecavir plasma concentrations and the HBV DNA decay at the first and third month of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.